Brigatinib

Synonym(s): AP26113(Brigatinib);
5-Chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-2,4-pyrimidinediamiChemicalbookne

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Product Introduction

CAS Number	1197953-54-0
Purity	≥98%
Total impurity	≤2%
Single impurity	≤0.5%
Molecular Formula	C29H39ClN7O2P
Molecular Weight	584.09
Retesting period	12 months
Storage Condition	-20°C Sealed storage
COA/ROS/MSDS/MOA	Provided

Brigatinib is a medication used to treat certain types of lung cancer, specifically non-small cell lung cancer (NSCLC) that has a specific genetic mutation called anaplastic lymphoma kinase (ALK). It works by inhibiting the abnormal ALK protein, which can cause cancer cells to grow and divide. Brigatinib is taken orally in tablet form and is usually prescribed after other treatments have failed or stopped working. Common side effects of brigatinib may include nausea, diarrhea, fatigue, loss of appetite, and cough. More serious side effects may include high blood pressure, lung problems, and liver damage. Regular monitoring by a healthcare provider is important during treatment with brigatinib.