2-Chloro-3-nitrobenzoic Acid CAS 3970-35-2

Synonym(s):
2-Chloro-3-nitrobenzoic acid, 98% 5GR
2-Chloro-3-nitrobenzoic acid,98%
Chloro-3-nitrobenzoica

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Product Introduction

Product Introduction

Product Name	2-Chloro-3-nitrobenzoic acid
CAS Number	3970-35-2
Purity	≥99%
Total impurity	≤1%
Single impurity	≤0.5%
Molecular Formula	C7H4ClNO4
Molecular Weight	201.56
Retest period	12 months
Storage Condition	Store at room temperature
COA/ROS/MSDS/MOA	Provided

Chemical Name

2-Chloro-3-nitrobenzoic acid

The CAS number for 2-Chloro-3-nitrobenzoic acid is 3970-35-2

The Molecular Formula of 2-Chloro-3-nitrobenzoic acid is C7H4ClNO4

Keywords

2-Chloro-3-nitrobenzoic acid

CAS 3970-35-2

APPLICATION

2-Chloro-3-nitrobenzoic acid is mainly used in the synthesis of the following classes of drugs or active molecules:

Synthesis of Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
* Anthranilic acid derivatives: 2-Chloro-3-aminobenzoic acid is obtained by reducing its nitro group. This compound is a key intermediate in the synthesis of certain fenamic acid-based NSAIDs (such as mefenamic acid and flufenamic acid). These drugs are mainly used for analgesia, anti-inflammation, and antipyresis.

Synthesis of Antibacterial Drugs
* Quinolone Antibacterial Drugs: In the synthetic route of quinolone drugs, 2-chloro-3-nitrobenzoic acid or its derivatives can be used as part of the quinolone core. Its benzene ring structure, the positioning effect of the chlorine atom and the nitro group are crucial for introducing key pharmacophore groups such as piperazine.

Other Antibacterial Molecules: Its structure is also used to synthesize some heterocyclic compounds with antibacterial activity, such as benzoxazole and benzimidazole.

Development of Antitumor Drugs
This compound and its derivatives are frequently used as starting materials for the synthesis of targeted anticancer drugs such as tyrosine kinase inhibitors and tubulin inhibitors. Its molecular framework can be cleverly modified to bind to specific cancer targets.

Other Pharmaceutical Fields
Synthetic pathways using 2-chloro-3-nitrobenzoic acid as an intermediate have also been discovered in the synthesis of antidepressants, anticonvulsants, and pesticides (such as herbicides and insecticides).

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