Ruxolitinib Intermediate CAS 3680-69-1
Ruxolitinib Intermediate CAS 3680-69-1

Ruxolitinib Intermediate CAS 3680-69-1

Synonym(s):
3-d)pyrimidine,4-chloro-7h-pyrrolo
4-Chloropyrrolo[2,3-d]pyrimidine 4-Chloro-1H-pyrrolo[2,3-d]pyrimidine

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Product Introduction

Product Introduction

Product Name	4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
Product Description	White powder
CAS Number	3680-69-1
Purity	≥99%
Total impurity	≤2%
Single impurity	≤0.5%
Molecular Formula	C6H4ClN3
Molecular Weight	153.57
Retest period	12 months
Storage Condition	Room Temperature
COA/ROS/MSDS/MOA	Provided

Chemical Name

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine is the intermediate of Ruxolitinib

The Product Description of Ruxolitinib Intermediate CAS 3680-69-1 is White powder

The Molecular Formula of Ruxolitinib Intermediate CAS 3680-69-1 is C6H4ClN3

Keywords

Ruxolitinib Intermediate CAS 3680-69-1

CAS 3680-69-1

APPLICATION

Ruxolitinib Intermediate (CAS 3680-69-1) is a pharmaceutical intermediate commonly used in the synthesis of ruxolitinib butyrate, a drug used to treat myeloproliferative diseases (such as myelofibrosis) and multiple myeloma .

Ruxolitinib butyrate is a drug that specifically inhibits Janus kinase (JAK) 1 and JAK2. These two kinases are involved in the regulation of physiological processes such as cell proliferation, development, and immune response. The drug can alleviate clinical symptoms and disease progression by inhibiting cell proliferation, inflammatory response, and immune response induced by pathogens.

The drug can significantly improve patient quality and longevity and was approved by the FDА as a routine treatment for myeloproliferative diseases. At the same time, ruxolitinib butyrate can also be used to treat other types of diseases, such as aplastic anemia and pulmonary fibrosis after hematopoietic stem cell transplantation.

In summary, Ruxolitinib Intermediate (CAS 3680-69-1) is an important pharmaceutical intermediate that provides necessary raw materials for the production of ruxolitinib butyrate. Ruxolitinib butyrate is a safe and effective drug that can significantly reduce clinical symptoms and improve patients' quality of life and longevity when treating a variety of diseases.

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