2-Fluoro-4-nitrobenzoic Acid CAS 403-24-7

Synonym(s):
2-Fluoro-4-nitrobenzoic acid 98+%
4-Carboxy-3-fluoronitrobenzene
2-Fluor-4-nitrobenzoic acid

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Product Introduction

Product Introduction

Product Name	2-Fluoro-4-nitrobenzoic acid
Product Description	Light yellow powder
CAS Number	403-24-7
Purity	≥99%
Total impurity	≤1%
Single impurity	≤0.5%
Molecular Formula	C7H4FNO4
Molecular Weight	185.11
Retest period	12 months
Storage Condition	Store at room temperature
COA/ROS/MSDS/MOA	Provided

Chemical Name

2-Fluoro-4-nitrobenzoic acid

The CAS number for 2-Fluoro-4-nitrobenzoic acid is 403-24-7

The Molecular Formula of 2-Fluoro-4-nitrobenzoic acid is C7H4FNO4

Keywords

2-Fluoro-4-nitrobenzoic acid

CAS 403-24-7

APPLICATION

2-Fluoro-4-nitrobenzoic acid is an important pharmaceutical intermediate. Its functional groups such as benzene ring, fluorine atom and nitro group in its structure give it diverse reactivity and can be used to synthesize a variety of biologically active compounds. The following are its main application directions in the pharmaceutical field:

1. Anti-tumor drugs:

Targeted drugs: Fluorine atoms and nitro groups can act as hydrogen bond acceptors and donors to bind to target proteins and improve the selectivity and activity of drugs. For example, it can be used to synthesize targeted anti-tumor drugs such as tyrosine kinase inhibitors.

Chemotherapeutic drugs: The benzene ring structure can be embedded in DNA, interfering with DNA replication, thereby inhibiting tumor cell growth. For example, it can be used to synthesize fluorouracil chemotherapy drugs.

2. Antibacterial drugs:

Quinolone antibiotics: Its structure can be used as the parent nucleus of quinolone antibiotics, such as the synthesis of broad-spectrum antibacterial drugs such as norfloxacin and ciprofloxacin.

Nitroimidazole antibiotics: Their nitro group can be reduced in an anaerobic environment to produce products with antibacterial activity, such as synthetic anti-anaerobic drugs such as metronidazole and tinidazole.

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